Three womb-to-tomb best friend know as “The Supremes” portion the unbreakable chemical bond of sistership from decade of weather life’s storm. Through the joy and sorrow of life, matrimony and child, felicity and blues, love and loss, new sunglasses of grief and unwellness threaten to stir up the past times when the three see their chemical bond put to the trial as they confront their to the highest degree ambitious times yet.